A Definitive Cause and Effect by a Multifunctional Protein
June 12, 2022
As has been previously discussed, the Spike Protein of SARS-CoV-2 has prion-like domains.
When these spike proteins are cleaved, released into the bloodstream or travel via extracellular vesicles, they become, in effect (among many other pathological initiators), ANCHORLESS PRIONS.
Anchorless prions are very pathogenic in humans. There have been reports of cases of human prion disease, which developed BECAUSE OF EXPRESSION OF ANCHORLESS C-TERMINALLY TRUNCATED PrP. The presence of one of the stop codon mutations Y145X, Q160X, Y163X, Y226X or Q227X results in spontaneous neurological illness, characterized by large PrP amyloid deposit. The mentioned mutations in humans RESULT IN PRION PROTEIN CEREBRAL AMYLOID ANGIOPATHY.
However, KEEP FOCUS. The POINT is that the SPIKE PROTEIN has PRION-LIKE DOMAINS. Therefore, you would not see “prion protein cerebral amyloid angiopathy.” Rather, you would observe Spike Protein Cerebral Amyloid Angiopathy.
Indeed, this is occurring.
A case study from October 2021 in the Journal of Neurological Sciences showed that Cerebral Amyloid Angiopathy had occurred in a 77-year old male post BNT162b2 vaccination.
What I find most disturbing about the brief study is that all that is discussed is a reaction to SARS-CoV-2 antibodies. Why is a pathology induced by the actual spike protein itself not investigated?
There is much mystery surrounding the Prion Protein. Yet, I cannot help but be fascinated by the similarities that it has with the Spike Protein. Beyond the shared domains.
PrPC most certainly can be regarded as a ‘multifunctional protein’ as interactions with PrP have been shown for oligomers of Amyloid-β (Aβ), tau, and α-synuclein, which are critically associated with Alzheimer’s disease (AD), frontotemporal dementia and other tauopathies, or Parkinson’s disease. All COVID related, of course.
As Fang Li began his review of coronavirus spike proteins in September of 2016: The coronavirus spike protein is a multifunctional molecular machine.