SPIKE PROTEIN ANTIBODY Fc DOMAIN AND CD32B

September 18, 2021

SPIKE PROTEIN ANTIBODIES AND IMPAIRED INTERFERON RESPONSE VIA AFFINITY FOR CD32B RECEPTORS: THERAPY (PERHAPS ESPECIALLY THIRD+ DOSE) DANGERS

The spike protein antibodies do indeed have a strong affinity for the SARS-CoV-2 spike protein. Very disturbingly, however, in some number, at least in severe cases, their Fc domain (other end of the antibody) also has a strong affinity for the CD32B receptor. If this receptor is agonized, then it tells the cell “Hey, it’s all good. You don’t have to defend anything, nothing to see here, carry on.” It lies to the cell (in precisely the same way many have lied to us) and the cell does NOT engage its Interferon response. This is the response that DOES tell the cell “Danger, Will Robinson!” and the cell goes into defense mode.

In a paper in Nature, the authors report that individuals with severe COVID-19 have anti-spike antibodies in which a region of the antibody, called the Fc domain, binds to CD32B. This interaction hinders the expression of interferon-regulated genes.

A UNIVERSITY’S PUBLICATION’S LIE, A SCANDAL TO HIDE THIS FACT

Please note that the USCF Magazine’s SUMMER 2021 Journal article on this mechanism readily admits that CD32B is being agonized in SARS-CoV-2 infection, yet they claim it is caused by an “unknown” antibody. The paper I previously referenced PROVED this in February of 2021. Clearly, they are lying so as to not cause the alarm that SHOULD MOST CERTAINLY be caused by the fact that Spike Protein antibodies are causing people to NOT have an adequate innate immune response to a pathogen.

The February paper concludes that this needs further research and does it happen in other diseases. The answer, I believe, is yes, it does. It was discovered recently that in Dengue infection, the very same receptor CD32B is extremely upregulated in severe infection.

I do not wish to consider the reasons behind giving only the elderly and at risk a therapy which, while going into winter, may compromise and/or further compromise their body’s innate immune response to pathogens.

Referenced/Related Papers

Your Immune System Could Turn COVID-19 Deadly

https://magazine.ucsf.edu/your-immune-system-could-turn-covid-19-deadly

Immune responses after dengue virus infection: friend or foe? by Dr. Tineke Cantaert

https://www.youtube.com/watch?v=LJRUqdx8Z6M&ab_channel=GLOBALIMMUNOTALKS

Some antibodies can dampen antiviral defences in people with severe COVID

https://www.nature.com/articles/d41586-021-00352-0