Severe COVID-19 and Ganglion Cell Layer Thinning

The COVID-induced disease I have discovered, Cholinergic Neuron Degeneration Disease, is indeed, the cause of severe COVID. 

Are Ganglion Cell Layer Thinning along with S Protein Load the factors which determine onset? If so, is it irreversible/prog?

Referenced/Related Papers

Autonomic balance determines the severity of COVID-19 courses

https://bioelecmed.biomedcentral.com/articles/10.1186/s42234-020-00058-0