February 7, 2021
The Spike Protein of the SARS-COV-2 virus is almost certainly a Superantigen.
https://pnas.org/content/117/41/25254
There have been several documented cases of recurrent Toxic Shock Syndrome.
Recurrent Nonmenstrual Toxic Shock Syndrome: Clinical Manifestations, Diagnosis, and Treatment
https://academic.oup.com/cid/article/32/10/1470/466771
Note that the two requirements for recurrent toxic shock are the persistence of the Superantigen and the absence of neutralizing antibodies. Also note, children present with MIS-C at precisely the time that neutralizing antibodies to SARS-CoV-2 may wane. 1-3 weeks.
This is almost certainly proof that SARS-CoV-2 is a persistent, neurotropic infection in some.
The MILLION DOLLAR QUESTION. What turns an asymptomatic infection into a life-threatening Toxic Shock Syndrome weeks later????
Referenced/Related Papers
Sustained Positivity and Reinfection With SARS-CoV-2 in Children: Does Quarantine/Isolation Period Need Reconsideration in a Pediatric Population?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732141/
Toxic shock syndrome. Possible confusion with Kawasaki's disease