The Unfolded Protein Response
January 24, 2021
Long Haulers may never see resolution of their condition. This is why all tests seem normal. The numbers are correct but the cells are genetically damaged.
The cells no longer work correctly. This is why Type 1 Diabetes is appearing post-COVID. The same misfolded white blood cells can also induce CJD.
It is also causing Light Chain Amyloidosis. This is Long COVID.
At some point during SARS-CoV-2 infection, the body can no longer resist the Endoplasmic Reticulum stress and the changes become permanent. COVID-19 is compromising the Endoplasmic Reticulum chaperones.
Referenced/Related Papers
DNA misfolding in white blood cells increases risk for type 1 diabetes
https://www.sciencedaily.com/releases/2020/02/200211121506.htm
Prion proteins in subpopulations of white blood cells from patients with sporadic Creutzfeldt-Jakob disease
https://ncbi.nlm.nih.gov/pmc/articles/PMC2786774/
Roles of spike protein in the pathogenesis of SARS coronavirus