SARS-CoV-2 AS A VIRAL NEUROTOXIN

March 29, 2021

SARS-CoV-2 IS A VIRAL NEUROTOXIN VERY SIMILAR TO RICIN. THERE IS A DOSE WHICH IS 100% FATAL AND UNTREATABLE.

In a Rhesus Macaque study of Ricin exposure, all monkeys had multifocal to coalescing fibrinopurulent pneumonia. This has been observed in COVID-19: Lung pathology of COVID-19: is (Acute Fibrinous and Organizing Pneumonia) AFOP in play?

Also, in Ricin poisoning purulent mediastinal lymphadenitis occurs. This is observed in Severe COVID cases, which emphasizes the dose-dependent factor of SARS-CoV-2 infection. 

Neurologically, Ricin immunologically impairs arcuate neurons in the hypothalamus. They release Neuropeptide Y. What does this cause? Interestingly, it causes, among other reactions, reduced pain perception, decreased food intake and alterations of the CIRCADIAN RHYTHM. Ricin also induces DNA fragmentation and inhibits protein synthesis. As with SARS-CoV-2 Ricin's translocation is preceded by endocytic uptake of the toxin and retrograde traffic through the trans-Golgi network (TGN) and the endoplasmic reticulum (ER). 

Ricin induces intracellular signaling which can induce BOTH cancer and neurodegenrative diseases such as Prion Disease, Parkinson's and Alzheimer's. 

Referenced/Related Papers

PulmCrit Wee: Lung pathology of COVID-19: is AFOP in play?

https://emcrit.org/pulmcrit/covid-afop/

Pathology of Lethal and Sublethal Doses of Aerosolized Ricin in Rhesus Macaques

https://ncbi.nlm.nih.gov/pmc/articles/PMC3849233/

Mediastinal lymphadenopathy in patients with severe COVID-19

https://thelancet.com/journals/laninf/article/PIIS1473-3099(20)30310-8/fulltext

The immunological impairment of arcuate neuropeptide Y neurons by ricin A chain produces persistent decrease of food intake and body weight

https://sciencedirect.com/science/article/abs/pii/030645229400573N

Neuropeptide Y

https://en.wikipedia.org/wiki/Neuropeptide_Y

Macrophage adherence prevents apoptosis induced by ricin

https://pubmed.ncbi.nlm.nih.gov/7925496/

Intracellular Transport and Cytotoxicity of the Protein Toxin Ricin

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628406/

Ricin and Shiga Toxins: Effects on Host Cell Signal Transduction

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7120278/

A novel swine model of ricin-induced acute respiratory distress syndrome

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312011/